E-mail: oprinczl@uwo.ca
Website: https://www.researchgate.net/profile/Oren-Princz-Lebel
Research Projects:
My research strives to understand how cell populations within the striatum support cognition in states of health and disease. To do so, I use cutting-edge in vivo techniques such as fibre photometry and genetically-encoded biosensors to record neuromodulator activity as animals perform complex touchscreen-based cognitive tasks. Furthermore, I am interested in understanding how striatal cells are affected in neurodegenerative diseases like Parkinson’s disease (PD). Cognitive impairments are common complications of PD, and are often distressing for both PD patients and their caregivers. Collaborating between the preclinical TCN Lab and the clinical MacDonald Lab, I hope to gain a better understanding of why these impairments occur and develop behavioural paradigms that promote better translation of findings across model organisms and patient populations