Postdoctoral Superstar Paul Sheppard
Our postdoc Paul is on a roll: giving talks, presenting posters, wining awards, and even publishing a paper! Join us...
Metabolic hormones mediate cognition
Abstract Recent biochemical and behavioural evidence indicates that metabolic hormones not only regulate energy intake and nutrient content, but also...
Decision Making in Mice During an Optimized Touchscreen Spatial Working Memory Task Sensitive to Medial Prefrontal Cortex Inactivation and NMDA Receptor Hypofunction
Abstract Working memory is a fundamental cognitive process for decision-making and is a hallmark impairment in a variety of neuropsychiatric...
Perspectives on Cognitive Phenotypes and Models of Vascular Disease
New publication by lab PI Tim Bussey and fellow collaborators!Abstract: Clinical investigations have established that vascular-associated medical conditions are significant...
The spontaneous location recognition task for assessing spatial pattern separation and memory across a delay in rats and mice
New TCNLab publication is out! Abstract Keeping similar memories distinct from one another is a critical cognitive process without which...
Using touchscreen-delivered cognitive assessments to address the principles of the 3Rs in behavioral sciences
Abstract Despite considerable advances in both in silico and in vitro approaches, in vivo studies that involve animal model systems...
Touchscreen Cognitive testing: Cross-Species Translation and Co-Clinical Trials in Neurodegenerative and Neuropsychiatric Disease
Abstract Translating results from pre-clinical animal studies to successful human clinical trials in neurodegenerative and neuropsychiatric disease presents a significant...
Age-dependent and region-specific alteration of parvalbumin neurons, perineuronal nets and microglia in the mouse PFC and hippocampus following obesogenic diet consumption
Abstract Emergent evidence demonstrates that excessive consumption of high fat and high sugar (HFHS) diets has negative consequences on hippocampal...
New Frontiers in Translational Research: Touchscreens, Open Science, and the Mouse Translational Research Accelerator Platform (MouseTRAP)
Abstract Many neurodegenerative and neuropsychiatric diseases and other brain disorders are accompanied by impairments in high‐level cognitive functions including memory,...
MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment.
Authors: Flavio H Beraldo, Daniel Palmer, Sara Memar, David I Wasserman, Wai-Jane V Lee, Shuai Liang, Samantha D Creighton, Benjamin...